1
عمومی::
لوب گیجگاهی
A PET study in human subjects to whom remifent- anil, 0.05 and 0.15 痢/kg/min, was administered revealed increases in CBF in the prefrontal, inferior parietal, and sup- plementary motor cortices; reductions in CBF were observed in the cerebellum, superior temporal lobe, and midbrain gray matter.105 The relative increase in CBF was greater with the administration of the larger dose of remifentanil.
In patients with temporal lobe epilepsy, the administration of 1.5 MAC sevoflurane elicited widespread paroxysmal EEG activity.
Accordingly, this anesthetic has been used to activate seizure foci during cortical mapping.211 In neurosurgical patients to whom larger doses of methohexital were admin- istered to produce burst suppression of the EEG, refractory seizures have occurred.215 Consequently, it appears that patients with seizures of temporal lobe origin, typically of the psychomotor variety or those to whom large doses are administered, are at risk for seizure activation by metho- hexital.
Partial complex seizures on the induction of anesthesia with fentanyl in patients undergoing anterior temporal lobectomy have been reported.228 Eight of the nine patients displayed electrical seizure activity at a range of clinically relevant fentanyl doses (mean, 26 痢/kg).228 Another study found that alfentanil, 50 痢/kg, augmented temporal lobe spike activity in patients with temporal lobe epilepsy.229 Untreated rigidity may, itself, also have impor- tant CNS consequences.
واژگان شبکه مترجمین ایران